Function of L-Pipecolic Acid as Compatible Solute in Corynebacterium glutamicum as Basis for Its Production Under Hyperosmolar Conditions
نویسندگان
چکیده
منابع مشابه
Introducing ectoine as compatible solute: biosynthetic pathway, production and applications
Halophilic microorganisms cope with environmental stresses by producing and accumulating compatible solutes. Ectoine is one of the most important members of compatible solutes which have extra protective properties compared to other compatible solutes. Ectoine attracts several scientific and commercial attention because of their multiple industrial applications. This brief review presents appli...
متن کاملEngineering of Corynebacterium glutamicum for high-yield L-valine production under oxygen deprivation conditions.
We previously demonstrated efficient L-valine production by metabolically engineered Corynebacterium glutamicum under oxygen deprivation. To achieve the high productivity, a NADH/NADPH cofactor imbalance during the synthesis of l-valine was overcome by engineering NAD-preferring mutant acetohydroxy acid isomeroreductase (AHAIR) and using NAD-specific leucine dehydrogenase from Lysinibacillus sp...
متن کاملTranscriptional profiling of Corynebacterium glutamicum metabolism during organic acid production under oxygen deprivation conditions.
A transcriptional profiling of the metabolism of Corynebacterium glutamicum under oxygen deprivation conditions is reported. It was observed that the glucose consumption rate per cell when C. glutamicum cells were incubated under oxygen deprivation conditions was higher than that achieved by cells incubated under aerobic growth conditions. Furthermore, DNA microarray and quantitative RT-PCR ana...
متن کاملStructural basis for cytokinin production by LOG from Corynebacterium glutamicum
"Lonely guy" (LOG) has been identified as a cytokinin-producing enzyme in plants and plant-interacting fungi. The gene product of Cg2612 from the soil-dwelling bacterium Corynebacterium glutamicum was annotated as an LDC. However, the facts that C. glutamicum lacks an LDC and Cg2612 has high amino acid similarity with LOG proteins suggest that Cg2612 is possibly an LOG protein. To investigate t...
متن کاملSignificance of the Corynebacterium Glutamicum Msccg Mechanosensitive Channel in Fine-tuning of Compatible Solute Accumulation
Accessible online at: www.karger.com/cpb SIGNIFICANCE OF THE CORYNEBACTERIUM GLUTAMICUM MSCCG MECHANOSENSITIVE CHANNEL IN FINE-TUNING OF COMPATIBLE SOLUTE ACCUMULATION Kirsten Börngen1, Andrew R. Battle2,3, Nina Möker1, Susanne Morbach1, Kay Marin1, Boris Martinac3 and Reinhard Krämer1 1University of Cologne, Köln, Germany, 2Griffith University, Parklands, Queensland, Australia, 3Victor Chang C...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2019
ISSN: 1664-302X
DOI: 10.3389/fmicb.2019.00340